Transforming Growth Factor-Beta in Cancer Therapy, Volume I
Produktnummer:
18a287d72a2ff14e2ab6ba9de2024edd4d
| Themengebiete: | Carcinom biological functions genes gene therapy physiology signal transduction transcription |
|---|---|
| Veröffentlichungsdatum: | 28.02.2008 |
| EAN: | 9781588297143 |
| Sprache: | Englisch |
| Seitenzahl: | 735 |
| Produktart: | Gebunden |
| Herausgeber: | Jakowlew, Sonia B. |
| Verlag: | Humana Press |
| Untertitel: | Basic and Clinical Biology |
Produktinformationen "Transforming Growth Factor-Beta in Cancer Therapy, Volume I"
Transforming Growth Factor-jl in Cancer Therapy, Volume I: Basicand Clinical Biology The present volume brings together a wealth of information that is fundamental to understanding the roleofTGF-~ in the pathogenesis, prevention, and treatment of cancer. It is not even 25 years sinceTGF-~ was first isolated and characterized as a dimeric pep tide from both human and bovine sources (1-3), but the entire fieldofTGF-~ research has grown and expanded so that it is now a central theme in all of cell biology. There is almost no tissue or organ in the mammalian body in whichTGF-~ does not playa central role in embryonic differentiation or in adult function, and furthermore, malfunction of the normal physiologyofTGF-~can have disastrous consequences in almost all ofthese sites. Therefore, the present comprehensive review of so many aspects ofTGF-~ function is a most welcome attempt to bring together a huge body of experimental data that is of the utmost importance in the field of oncology.
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