Phenotypes and Genotypes
Frommlet, Florian, Bogdan, Malgorzata, Ramsey, David
Produktnummer:
18bafa5326e87248e2af2609e297fa13ed
| Autor: | Bogdan, Malgorzata Frommlet, Florian Ramsey, David |
|---|---|
| Themengebiete: | Association Mapping Gene Mapping Genome Wide Association Studies (GWAS) Quantitative Trait Loci (QTL) Trait Loci (TL) |
| Veröffentlichungsdatum: | 24.02.2016 |
| EAN: | 9781447153092 |
| Sprache: | Englisch |
| Seitenzahl: | 222 |
| Produktart: | Gebunden |
| Verlag: | Springer London |
| Untertitel: | The Search for Influential Genes |
Produktinformationen "Phenotypes and Genotypes"
This timely text presents a comprehensive guide to genetic association, a new and rapidly expanding field that aims to elucidate how our genetic code (genotypes) influences the traits we possess (phenotypes). The book provides a detailed review of methods of gene mapping used in association with experimental crosses, as well as genome-wide association studies. Emphasis is placed on model selection procedures for analyzing data from large-scale genome scans based on specifically designed modifications of the Bayesian information criterion. Features: presents a thorough introduction to the theoretical background to studies of genetic association (both genetic and statistical); reviews the latest advances in the field; illustrates the properties of methods for mapping quantitative trait loci using computer simulations and the analysis of real data; discusses open challenges; includes an extensive statistical appendix as a reference for those who are not totally familiar with the fundamentals of statistics.
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