Pharmacokinetic Challenges in Drug Discovery
Produktnummer:
18f4b431fe937c4d24ab7741914b87b96b
Themengebiete: | Drug Metabolism Pharmocokinetics absorption cytochrome P450 drug drug development drug discovery drug research kinetics metabolism |
---|---|
Veröffentlichungsdatum: | 16.12.2012 |
EAN: | 9783662043851 |
Sprache: | Englisch |
Seitenzahl: | 306 |
Produktart: | Kartoniert / Broschiert |
Herausgeber: | Baumann, A. Pelkonen, O. Reichel, A. |
Verlag: | Springer Berlin |
Produktinformationen "Pharmacokinetic Challenges in Drug Discovery"
Despite increased spending on research and development, the number of new medicines marketed successfully continues to decline. The Pharmaceutical industry is therefore focussing on ways to reduce attrition by addressing frequent reasons for clinical drug failures very early in the drug discovery process. One of the biggest challenges is the pharmacokinetic (PK) optimisation of drug candidates tailored and predicted to have appropriate absorption, distribution, metabolism and excretion (ADME) characteristics in human. This book describes how traditional pbarmacokinetic approaches and methods are being re-invented' to meet specific needs dictated by the dynamics of the drug discovery process. The book gives an overview of state-of-the-art tools and their use in the decision-making process is discussed by a number of scientists from leading pharmaceutical companies.

Sie möchten lieber vor Ort einkaufen?
Sie haben Fragen zu diesem oder anderen Produkten oder möchten einfach gerne analog im Laden stöbern? Wir sind gerne für Sie da und beraten Sie auch telefonisch.
Juristische Fachbuchhandlung
Georg Blendl
Parcellistraße 5 (Maxburg)
8033 München
Montag - Freitag: 8:15 -18 Uhr
Samstags geschlossen