NMR of Glycoproteins
Produktnummer:
18d6a526057add459a9a9d8365cac2b788
Themengebiete: | CRISPR cas isotope labeling oligosaccharides soluble glycoproteins tailored glycosylation |
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Veröffentlichungsdatum: | 07.09.2025 |
EAN: | 9781071647219 |
Sprache: | Englisch |
Seitenzahl: | 210 |
Produktart: | Gebunden |
Herausgeber: | Jiménez-Barbero, Jesús Millet, Oscar |
Verlag: | Springer US |
Untertitel: | Methods and Protocols |
Produktinformationen "NMR of Glycoproteins"
This volume explores the latest advancements in the field of Nuclear Magnetic Resonance (NMR) and discusses how new studies provide insight into the structure, conformation, dynamics, and interactions of glycoproteins. The chapters in this book covers topics such as the preparation of isotope-labeled eukaryotic glycoproteins; applications of paramagnetic NMR to dissect glycosaminoglycan-protein interactions; interactions of mucin glycoproteins; applications of NMR to decipher the interactions between viral proteins and the glycans on host cells; NMR methods to identify biomarkers based on the glycoprotein signals directly acquired from intact biofluids; and the applications of MD simulations and other computational methods to characterize the conformation and dynamics of glycoproteins. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and thorough, NMR of Glycoproteins: Methods and Protocols is a valuable resource for both new and experienced researchers who want to learn more about this important and developing field.

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