New Strategies for N-Heterocyclic Carbenes Catalyzed Annulations
Chen, Xiangyu
Produktnummer:
185e7d507d987547c3aabaee29f25dc0f3
| Autor: | Chen, Xiangyu |
|---|---|
| Themengebiete: | Annulations Enantioselective synthesis Heterocycles N-heterocyclic Carbenes Organocatalysis |
| Veröffentlichungsdatum: | 07.07.2018 |
| EAN: | 9789811097348 |
| Sprache: | Englisch |
| Seitenzahl: | 123 |
| Produktart: | Kartoniert / Broschiert |
| Verlag: | Springer Singapore |
Produktinformationen "New Strategies for N-Heterocyclic Carbenes Catalyzed Annulations"
This thesis focuses on NHC-catalyzed annulation of nitroalkenes, enals and a,ß-unsaturated carboxylic acids. (1) NHCs were found to be efficient catalysts for the [4+2] annulation of ß-substituted nitroalkenes. The scope of Rauhut–Currier reaction was successfully extended to the most challenging ß-substituted alkenes by this method; (2) Enals were successfully used for [4+2] annulations with azodicarboxylates catalyzed by NHC via ?-addition. Highly enantiopure tetrahydropyridazinones and ?-amino acid derivatives could be easily prepared by subsequent transformations of the resulting dihydropyridazinones. (4) The readily available a,ß-unsaturated carboxylic acids were first successfully employed to generate the a,ß-unsaturated acyl azolium intermediates by using NHC for the enantioselective [3+2] and [3+3] annulations.
Sie möchten lieber vor Ort einkaufen?
Sie haben Fragen zu diesem oder anderen Produkten oder möchten einfach gerne analog im Laden stöbern? Wir sind gerne für Sie da und beraten Sie auch telefonisch.
Juristische Fachbuchhandlung
Georg Blendl
Parcellistraße 5 (Maxburg)
8033 München
Montag - Freitag: 8:15 -18 Uhr
Samstags geschlossen