Neuroanatomy and Pathology of Sporadic Alzheimer's Disease
Braak, Heiko, Del Tredici, Kelly
Produktnummer:
184fd2a3bb338147d18809f448b02debbd
Autor: | Braak, Heiko Del Tredici, Kelly |
---|---|
Themengebiete: | amyloid precursor protein argyophilic lesions neurofibrillary changes non-Alzheimer disorder plaque-like formations tauopathies |
Veröffentlichungsdatum: | 23.12.2014 |
EAN: | 9783319126784 |
Sprache: | Englisch |
Seitenzahl: | 162 |
Produktart: | Kartoniert / Broschiert |
Verlag: | Springer International Publishing |
Produktinformationen "Neuroanatomy and Pathology of Sporadic Alzheimer's Disease"
As indicated by its title, this monograph deals chiefly with morphologically recognizable deviations from the normal anatomical condition of the human CNS. The AD-associated pathology is illustrated from its beginnings (sometimes even in childhood) to its final form, which is reached late in life. The AD process commences much earlier than the clinically recognizable phase of the disorder, and its timeline includes an extended preclinical phase. The further the pendulum swings away from the symptomatic final stages towards the early pathology, the more obvious the lesions become, although from a standpoint of severity they are more unremarkable and thus frequently overlooked during routine neuropathological assessment. For this reason, the authors deal with the hallmark lesions in the early phases of the AD process in considerable detail

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