Improving the Therapeutic Ratio in Head and Neck Cancer
| Themengebiete: | Science |
|---|---|
| Veröffentlichungsdatum: | 05.10.2019 |
| EAN: | 9780128178683 |
| Sprache: | Englisch |
| Seitenzahl: | 376 |
| Produktart: | Gebunden |
| Herausgeber: | Bonavida, Benjamin |
| Verlag: | Elsevier Science |
| Untertitel: | Volume 6 |
Produktinformationen "Improving the Therapeutic Ratio in Head and Neck Cancer"
Improving the Therapeutic Ratio in Head and Neck Cancer provides a complete review of current approaches to modulating therapeutic sensitivity in head and neck cancer. It presents a broad background of current approaches and by highlighting the potential for clinical translational, introduces a roadmap for how to move promising preclinical findings into the clinic. The book discusses topics such as immunotherapy and molecularly targeted therapies in head and neck cancer, PI3k/mTOR pathway, autophagy inhibition to sensitize HNC to radiation and chemotherapy, TAM and Eph/Ephrin family proteins and metabolic reprogramming to modulate therapeutic sensitivity. Additionally, it details approaches to improve the response to immunotherapy, and Chk1/2 inhibition in radiation and cetuximab resistance. This book is a valuable source to head and neck cancer researchers and advanced students, and to those studying specific approaches in other model systems and disease sites.
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