Handbook of HER2-targeted agents in breast cancer
Alvarez, Ricardo H, Cortés, Javier, Mattos-Arruda, Leticia, Falzon, Mary, Fasolo, Angelica, Gandy, Michael, Gianni, Luca, Harbeck, Nadia, Piccart, Martine, Zambelli, Stefania, Zardavas, Dimitrios
Produktnummer:
183be6e9928fbf48198887ac2bbab99d15
| Autor: | Alvarez, Ricardo H Cortés, Javier Falzon, Mary Fasolo, Angelica Gandy, Michael Gianni, Luca Harbeck, Nadia Mattos-Arruda, Leticia Piccart, Martine Zambelli, Stefania Zardavas, Dimitrios |
|---|---|
| Themengebiete: | Biomarkers Breast Cancer Cancer HER2 Oncology pharmacotherapy |
| Veröffentlichungsdatum: | 03.11.2014 |
| EAN: | 9781907673931 |
| Sprache: | Englisch |
| Seitenzahl: | 96 |
| Produktart: | Kartoniert / Broschiert |
| Verlag: | Springer Healthcare |
Produktinformationen "Handbook of HER2-targeted agents in breast cancer"
Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in women worldwide, accounting for nearly a quarter of the total new cancer cases each year. Of these cases, approximately 15–25% overexpress HER2, a transmembrane RTK kinase that is associated with aggressive tumor growth and poor outcomes. However, in the past decade, survival rates of patients with HER-positive breast cancer have significantly improved due to increased screening, HER2 testing, and breakthrough HER2-targeted drug therapies. Handbook of HER2-Targeted Agents in Breast Cancer provides oncologists, primary care physicians, trainees and other healthcare providers with a concise, accessible, and up-to-date survey of the field, including a review of our current understanding of the biology of the HER2 pathway and the rationale for targeting it in early-stage and advanced breast cancer, an overview of HER2-testing, and evidence-based discussions of available HER2-targeted regimens in the adjuvant and metastatic settings.
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