Dendritic Cells in Clinical Immunology

Dendritic cells are powerful antigen presenting cells which are significant for initiating the primary immune response. They travel to the lymph nodes when activated, where they interact with B and T cells to instigate and develop the adaptive immune response. They are the principal regulators of the immune system response and perform this function by linking the specificity of the adaptive response with the microbial sensing features of the innate immune system. Furthermore, these cells are effective in antigen presentation and are capable of acclimatizing to produce right amount of T cells as a response to a particular pathogen. Dendritic cells are also helpful in directing the immune system to react to foreign substances, simultaneously avoiding autoimmune responses. Altered function of dendritic cells is recognized to have a crucial role in autoimmune diseases and allergies, such as inflammatory bowel disease and lupus erythematosus. This book provides comprehensive insights into the role of dentritic cells in immunology. It is a valuable compilation of topics, ranging from the basic to the most complex advancements in this area of study. Those in search of information to further their knowledge will be greatly assisted by this book.