Computational Modeling of Drugs Against Alzheimer’s Disease
Produktnummer:
184a717f98d52645f8959bcbfb8b5de773
| Themengebiete: | AChE inhibitors ADMET optimization BACE CDK5/p25 Drug design Drug development GSK Pharmacology |
|---|---|
| Veröffentlichungsdatum: | 29.09.2017 |
| EAN: | 9781493974030 |
| Sprache: | Englisch |
| Seitenzahl: | 645 |
| Produktart: | Gebunden |
| Herausgeber: | Roy, Kunal |
| Verlag: | Springer US |
Produktinformationen "Computational Modeling of Drugs Against Alzheimer’s Disease"
This volume describes different computational methods encompassing ligand-based approaches (QSAR, pharmcophore), structure-based approaches (homology modeling, docking, molecular dynamics simulation), and combined approaches (virtual screening) with applications in anti-Alzheimer drug design. Different background topics like molecular etiologies of Alzheimer’s disease, targets for new drug development, and different cheminformatic modeling strategies are covered for completeness. Special topics like multi-target drug development, natural products, protein misfolding, and nanomaterials are also included in connection with computational modeling of anti-Alzheimer drug development. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory. Cutting-edge and authoritative, Computational Modeling of Drugs Against Alzheimer’s Disease is a valuable resource for learningabout the latest computational techniques used to study this disease.
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