Complement and Kidney Disease
Produktnummer:
186fd44ad9498a400d95d0bea46b9e21ca
| Themengebiete: | Complement system Kidney diseases biology diseases glomerulonephritis kidney membrane molecular biology mutation protein |
|---|---|
| Veröffentlichungsdatum: | 09.12.2005 |
| EAN: | 9783764371661 |
| Sprache: | Englisch |
| Seitenzahl: | 236 |
| Produktart: | Gebunden |
| Herausgeber: | Zipfel, Peter F |
| Verlag: | Springer Basel |
Produktinformationen "Complement and Kidney Disease"
It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinct human kidney diseases is caused by defective complement control. Genetic analyses have identified mutations in complement regulators that are associated with these diseases. Mutations have been identified in the fluid phase alternative pathway regulator Factor H and the membrane regulator Membrane Cofactor Protein MCP (CD46). The functional characterization of the mutant proteins allows to define the pathophysiological events on a molecular level. These new concepts and data on disease mechanisms allowed establishing new diagnostic and promising therapeutic approaches for several human kidney diseases. Molecular biology, clinics and therapy are discussed in this volume.
Sie möchten lieber vor Ort einkaufen?
Sie haben Fragen zu diesem oder anderen Produkten oder möchten einfach gerne analog im Laden stöbern? Wir sind gerne für Sie da und beraten Sie auch telefonisch.
Juristische Fachbuchhandlung
Georg Blendl
Parcellistraße 5 (Maxburg)
8033 München
Montag - Freitag: 8:15 -18 Uhr
Samstags geschlossen